Second allogeneic bone marrow transplants from unrelated donors for graft failure following initial unrelated donor bone marrow transplantation
نویسندگان
چکیده
منابع مشابه
Characterization of cells emerging at the time of graft failure after bone marrow transplantation from an unrelated marrow donor.
To help elucidate the mechanism responsible for graft failure (GF) following a T-cell depleted bone marrow transplant (BMT) from an unrelated donor, five patients (2 chronic myelogenous leukemia, 1 acute undifferentiated leukemia, 2 myelodysplastic syndrome) who experienced this complication were studied. All patients were HLA class I identical with their donors as determined by serology and on...
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There have been few reports on immune-mediated neurological disturbances and none on solitary occurrence of optic neuritis after bone marrow transplantation (BMT). We experienced a very rare case of immune-mediated optic neuritis as one symptom of graft-versus-host disease (GVHD). A 34-year-old man with chronic myelogenous leukemia in accelerated phase received BMT from a human leukocyte antige...
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There is little information available regarding the outcome of unrelated bone marrow transplantation (BMT) for non-Hodgkin lymphoma (NHL). Therefore, we retrospectively analyzed the data of 124 patients who underwent unrelated BMT through the Japan Marrow Donor Program (JMDP) between July 1992 and August 2001. The overall survival (OS), progression-free survival (PFS), cumulative incidences of ...
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BACKGROUND Randomized trials have shown that the transplantation of filgrastim-mobilized peripheral-blood stem cells from HLA-identical siblings accelerates engraftment but increases the risks of acute and chronic graft-versus-host disease (GVHD), as compared with the transplantation of bone marrow. Some studies have also shown that peripheral-blood stem cells are associated with a decreased ra...
متن کاملAllogeneic marrow grafting with partially mismatched, unrelated marrow donors.
Forty patients with advanced hematologic malignancies or severe aplastic anemia received marrow grafts from partially mismatched, unrelated marrow donors. All patients were administered conventional prophylaxis for acute graft-v-host disease (GVHD) consisting of methotrexate and low-dose glucocorticoids. All but two patients who survived at least 30 days showed durable engraftment. Six patients...
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ژورنال
عنوان ژورنال: Bone Marrow Transplantation
سال: 1998
ISSN: 0268-3369,1476-5365
DOI: 10.1038/sj.bmt.1701146